The Arabidopsis Book (TAB) was a free access peer-reviewed serial publication that was supported by the American Society of Plant Biologists. It was launched in 2002 under the direction of Chris Somerville and Elliot Meyerowitz as a new model for communicating up-to-date and comprehensive information about a broad range of topics in research on Arabidopsis thaliana and related species. New articles were published as fields evolved, and older content was substantively revised on an ongoing basis. In late 2010, approximately 80 articles had been published reflecting the breadth of research on Arabidopsis. Members of the community were encouraged to provide the Editorial Board with suggestions for new topics worthy of inclusion or in need of expansion or major updates.

Because of the variety of topics being covered and to take advantage of the web-only publication style, authors were encouraged to select article formats that best suit the topic being covered. For example, some articles that provided comprehensive reviews of broad fields relied heavily on dynamic links to databases or other resources designed specifically for the article or public domain resources such as community databases. In other cases, complex fields were covered in more summary or teaching-oriented formats. Many papers followed more traditional review-article formats. In all cases authors were expected to make use of hyperlinks to long-lived web resources to allow the reader easy access to information about genes, datasets, and other key references.

The Arabidopsis Book ceased publication at the end of 2019.